Depression can feel like a constant weight that impacts every part of your life. It can make even mundane activities feel difficult and cause you to lose interest in things you once enjoyed. Though many treatments are available, finding one that works for you can be challenging.
If you are still searching for relief from depression,
SPRAVATO may renew your hope for a long-awaited solution. Many people interested in this advanced treatment wonder, “What does SPRAVATO do?” At Hauser Clinic & Associates, our dedicated team has an extensive background in advanced mental health care. We are here to help you understand your treatment options, including what to expect with SPRAVATO.
What Is SPRAVATO?
SPRAVATO is gaining popularity as an effective treatment for those living with treatment-resistant depression (TRD), meaning they have not had success with other methods. It is administered as a nasal spray containing esketamine (the compound in ketamine), a powerful medication known for its ability to provide rapid relief from symptoms of depression.
Because of its effectiveness, SPRAVATO is approved by the Food and Drug Administration (FDA) to treat TRD as well as suicidal thoughts. It is best administered in phase-based sessions for optimal results. You will receive this treatment at our clinic twice a week for one month, then the frequency will gradually decrease based on your response. Each session will last about two hours, during which your mental and physical health will be carefully monitored by one of our qualified team members.
How Does SPRAVATO Work?
SPRAVATO acts on N-methyl-D-aspartate (NMDA) receptors in the brain, which work to rebalance chemicals that influence mood, emotional regulation, and cognition. It also boosts neuroplasticity, which is the brain’s ability to form and repair connections that may have weakened in those who have been battling depressive symptoms for a long time.
Based on real‑world data, 28 percent of patients reported that their symptoms improved within 24 hours of their first dose (Johnson & Johnson, 2025). For those who can tolerate antidepressants, combining this traditional medication with SPRAVATO sessions can produce even more transformative results.
Are You a Candidate for SPRAVATO?
As the only FDA-approved esketamine-based nasal spray currently available, SPRAVATO is a safe and generally well-tolerated treatment option for many patients. You may be a good candidate if you are experiencing TRD or suicidal thoughts and are seeking improvement in your mental health. Insurance providers typically require documentation showing that you have tried at least two antidepressants without meaningful symptom relief before they approve coverage.
While SPRAVATO enables many people to achieve lasting improvement in their mental health, it is not right for everyone. This nasal spray can raise blood pressure temporarily during treatment, so if you have certain conditions, such as uncontrolled hypertension, heart disease, or a history of aneurysms or brain bleeds, SPRAVATO may not be safe for you. Those with a history of substance abuse disorders may also not be the best candidates for this medication.
To find out if you are a candidate for SPRAVATO, we recommend that you schedule an initial consultation at our office. Here, one of our board-certified psychiatrists will ask you questions about your medical and psychiatric history, current symptoms, and goals for treatment. We can then determine whether SPRAVATO is a good fit for you and work together to create a personalized treatment plan that addresses your unique needs. If you do not end up being a candidate for SPRAVATO, we offer a wide range of services that treat the whole person and are here to provide you with alternatives better suited to your needs.
Contact Us Today To Learn More About What SPRAVATO Does
SPRAVATO can offer profound relief to those living with depression or suicidal thoughts. Choosing this treatment is an empowering way to reclaim your mental health and achieve long-term emotional stability. If you have been asking, "What does SPRAVATO do?"
contact us today to learn more, schedule your initial consultation, and begin your journey toward wellness.