Spravato FAQs

Spravato is emerging as a transformative way to improve mental health for those struggling with symptoms of depression. If you have tried traditional treatments, such as antidepressants, without success, this advanced therapy offers a path forward if you feel unable to progress on your journey toward wellness. Since Spravato is gaining popularity as an alternative treatment for depression, many people have questions about what Spravato is and how it can benefit them. At Hauser Clinic & Associates, our dedicated team can support you through your journey toward wellness, help you understand the benefits of Spravato, and explain what to expect from this treatment. Explore our Spravato FAQs and get in touch with us today.

Is Spravato FDA-Approved?

The FDA cleared Spravato for treatment-resistant depression (TRD) and suicidal ideation in adults. The FDA initially approved Spravato in 2019 as an adjunct therapy for those on oral antidepressants. In 2025, the FDA expanded its approval for Spravato as a monotherapy, which means it can serve as a standalone treatment for depressed patients who have not responded to antidepressants.

When Will You Feel Results?

Spravato offers rapid relief for those experiencing depressive or suicidal thoughts. Most patients in Bellaire report relief of depressive symptoms within 24 hours after their first dose of Spravato treatment. The fast-acting nature of this esketamine-based nasal spray makes it a unique and effective option for those who need quick symptom improvement.

Is Spravato Effective?

Extensive clinical data supports Spravato's effectiveness in treating symptoms of depression for those who have not felt meaningful relief from other methods (Johnson & Johnson, 2025). Spravato is most effective when administered on a phase-based dosing schedule, which includes treatments for several weeks that decrease in frequency over time. Our team will help you learn about the evidence-based dosing schedule for Spravato to achieve maximum efficacy in the treatment of depression.

Can You Drive After a Spravato Treatment?

Spravato contains esketamine, which is a sedative. This means that in addition to relief of depressive symptoms, you may experience temporary sleepiness, dizziness, or feelings of disconnection during and after your Spravato session. For these reasons, we require that our patients arrange for a safe ride home after their Spravato doses.

Who Is a Good Candidate for Spravato?

Good candidates for Spravato are typically adults with TRD who have tried at least two different types of antidepressants but did not achieve meaningful symptom relief. You may not be eligible for Spravato if you have a history of uncontrolled high blood pressure, aneurysms, or brain bleeds. If you have heart, brain, or liver problems, please let our team know so we can ensure your safety during treatments. If you are pregnant or breastfeeding, you should not take Spravato. The best way to know if you are a good candidate for Spravato is by scheduling an initial consultation. A psychiatrist will meet you to discuss your medical history and treatment goals. During the consultation, feel free to discuss your concerns and ask about the advantages of Spravato. Be sure to tell us all the medications you take, including:
  • Vitamins
  • Prescriptions
  • Recreational drugs
  • Herbal supplements
  • Over-the-counter meds
Our top priority is your safety and comfort, and knowing your current state of health will allow us to ensure Spravato is right for you.

Contact Our Bellaire Clinic To Get Answers About Spravato Treatment

If you are struggling with uncontrolled and burdensome symptoms of depression, Spravato is an empowering way to take control of your mental health and achieve renewed wellness. This advanced treatment restores hope if you are still searching for relief after not having had success with antidepressants. If you still have questions after reading our Spravato FAQs, our dedicated team is here to provide clarity. Reach out to us today.

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